The abuse of hydrocodone (Vicoden) is a major problem. Compounding the addiction issue is the toxicity of the acetaminophen contained in the drug. Users consume many times the safe amounts of acetaminophen attempting to experience the euphoric effects of hydrocodone. Acetaminophen is hepato-toxic. It damages the liver, leading to irreversible liver damage and death. The dangers are increased with underlying conditions such as alcoholism, malnourishment or dehydration. These conditions can lower the toxic threshold of the drug. A tolerance is developed; the physical addiction to the hydrocodone in the drug causes the user to require a higher dose to achieve the same effect. This increase in acetaminophen levels leads to acute liver toxicity, causing liver necrosis and cell death. Acetaminophen poisoning is the leading cause of liver damage resulting in liver transplantation in Britain, and has replaced viral hepatitis as the leading cause of acute hepatic failure in the U.S.
Hydrocodone Dangers
Hydrocodone is an opiate derivative. Addiction to hydrocodone is similar to heroin addiction. The addict experiences cravings, causing drug-seeking behavior. Hydrocodone is one of the most prescribed drugs in America. Doctor shopping is common among addicts, going from doctor to doctor in an attempt to obtain the drug. Withdrawal from Hydrocodone causes physical symptoms common to opiate withdrawal. Nausea, diarrhea, cramps and chills are experienced. In severe cases, seizures and death can occur. With the high tolerance that occurs in Hydrocodone addiction, users take as many as 50 or 60 pills a day. The average dose of acetaminophen in one pill is 500 mg. Toxicity level for an adult is approx 7-10g. The best way to prevent further damage to the hepatic system is to stop using. Rehab and counseling can aid in stopping the addiction.
Treatment for Hydrocodone Addiction
Treatment for Vicoden addiction is the same as for any other opiate. Withdrawal symptoms should be addressed before starting a rehab program. The addict should be kept under medical care at a detox center or medical facility until withdrawal symptoms subside. Liver tests should be performed to assess for liver damage. Counseling and group therapy are beneficial to address the root problem of the addiction. The easy availability of this drug poses a special problem for the recovering addict. The desire to stop using must be sincere. A strong support system goes a long way in successful recovery. Twelve-step programs offer excellent support for the recovering individual.
Source:
emedicine.medscape.com "Toxicity,Acetamenophen" (Accessed April, 8 2010)